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Yeast cells are useful to display screen for mutations that regulate γ-secretase exercise. while in the current analyze, we identified Aph1 mutants that have protease action from the absence of NCT. We observed that these mutants enhanced γ-secretase endoproteolysis exercise with whole subunits. We propose that the fundamental mutations induce conformational changes in PS1 to enhance protease action.

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Sejauh ini, Jokowi yang segera turun dari kursi presiden, dan Gibran yang bakal naik menjadi wakil presiden – sama-sama tak punya kendaraan politik, kata Aditya. Tapi keduanya masih punya ambisi untuk memiliki pengaruh.

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